084f2db8c6 Possible modes of action of the artemisinin-type compounds. The anti-malarial artesunate is also active ahainst cancer. Cancer Biol Ther 2008; 7: 1017–23.ArticlePubMedCASLu JJ, Meng LH, Shankavaram UT, Zhua CH, Tong LJ, Chen G, et al. It is instructive that the C-centered radicals derived from QHS and their derivatives could attack free cysteine and cysteine rasidue not only in peptide but also probably in protein.The outstanding characteristics of QHS, including high antimalarial action, less significant side effects and less clinical resistance, impelled researchers to extend its medical application. This page uses JavaScript to progressively load the article content as a user scrolls. The major products tetrahydrofuran 3 and 3-hydroxy deoxyqinghaosu 4 were proposed to be derived from primary C-centered free radical 1 and secondary C-centered free radical 2, respectively, as shown in Scheme 2. These products were separated and subjected to both bioassay and chemical reaction with ferrous ion. Zhou R, et al.
Suppressive effect of a novel water-soluble artemisinin derivative SM 905 on T cell activation and proliferation in vitro and in vivo. Synthesis and immunosuppressive activity of new artemisinin derivatives containing polyethylene glycol group. Trends Parasitol 2001; 17: 122–6.ArticlePubMedISICASPosner GH, O'Neill PM. Yao Xue Xue Bao 1981; 16: 429–39. 13C NMR revealed the presence of fifteen carbon signals, the numbers of primary, secondary, tertiary and quaternary carbon being 3, 4, 5 and 3, respectively. The program for new drugs or lead compounds from traditional Chinese medicine (TCM) and folk medicineOne of the various programs in the “Project 523” was a team for the “study and survey on effective folk medicine and therapy against malaria”. 10, Berlin, Germany More science events ADVERTISEMENT Top This journal is a member of and subscribes to the principles of the Committee on Publication Ethics.
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